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Journal of Biomedical Optics

Processing algorithms for tracking speckle shifts in optical elastography of biological tissues
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Paper Abstract

Parametric and nonparametric data processing schemes for analyzing translating laser speckle data used to investigate the mechanical behavior of biological tissues are examined. Crosscorrelation, minimum mean square estimator, maximum likelihood, and maximum entropy approaches are discussed and compared on speckle data derived from cortical bone samples undergoing dynamic loading. While it was not the purpose of this paper to demonstrate that one processing technique is superior to another, maximum likelihood and maximum entropy approaches are shown to be particularly useful when the observed speckle motion is small.

Paper Details

Date Published: 1 October 2001
PDF: 9 pages
J. Biomed. Opt. 6(4) doi: 10.1117/1.1412224
Published in: Journal of Biomedical Optics Volume 6, Issue 4
Show Author Affiliations
Donald Dean Duncan, Johns Hopkins Univ. (United States)
Sean J. Kirkpatrick, Providence St. Vincent Medical Ctr. (United States)


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