The Moscone Center
San Francisco, California, United States
7 - 12 February 2015
Conference 9318
Optical Biopsy XIII: Toward Real Time Spectroscopic Imaging and Diagnosis
Tuesday - Wednesday 10 - 11 February 2015
This conference is no longer accepting submissions.
Late submissions may be considered subject to chair approval. For more information, please contact SPIE
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Abstract Due:
28 July 2014

Author Notification:
6 October 2014

Manuscript Due Date:
12 January 2015

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Conference Chairs
Program Committee
  • Irving J. Bigio, Boston Univ. (United States)
  • Nicole J. Crane, Naval Medical Research Ctr. (United States)
  • Zhiwei Huang, National Univ. of Singapore (Singapore)
  • Amir Gandjbakhche, National Institutes of Health (United States)

Program Committee continued...
Call for
The goal of this conference is to present novel state-of-the-art work in non-invasive spectroscopic methods to detect the onset and progression of disease, including pre-malignancy and malignancy, and tissue and cells response to external conditions, including therapeutic intervention, unintended injury, and laser energy deposition. The conference will focus on work investigating the differences in single and multiphoton excitation optical signatures of normal and diseased tissues, and on understanding the underlying biochemical and structural changes of tissues and cells responsible for the observed spectroscopic signatures. It is worth noting that this symposium has hosted in recent years a number of contributions on the detection of disease using optical spectroscopy signatures of body fluids such as urine or blood plasma. As the field of metabolomics continues to grow, it is possible that “optical metabolomics” maybe a new frontier in the field of Optical Biopsy.

This conference covers a wide array of well-established optical techniques and novel approaches to diagnose tissues changes, including: in vivo and ex vivo fluorescence spectroscopy, Stokes shift spectroscopy, spectral imaging, Raman spectroscopy, multiphoton and photonic methods to modify the tissue and body fluids properties or functions implemented in vivo or ex-vivo covering the technology development steps from bench-to-bedside. Compact pill smart spectral explorers, multi-spectral imagers, coherence effects, and hyper spectral imaging will be highlighted and covered, in part, by speakers.

Topics include:
  • origin of tissue optical properties
  • NIR optical windows in 700 nm to 2500nm
  • optical methods for tissue diagnosis and treatment
  • methods for in vivo assessment of physiological state of tissue
  • excitation, absorption, fluorescence spectroscopy and imaging
  • Raman spectroscopy and imaging
  • inelastic light scattering spectroscopy and imaging
  • stimulated Raman gain spectroscopy and imaging
  • Stokes shift spectroscopy
  • polarization and diffusive reflectance spectral imaging
  • THz spectroscopy and imaging
  • phosphorescence spectroscopy and imaging
  • novel coherence methods
  • multi photon spectroscopy and imaging
  • upper excite states for deeper penetration in tissue and brain
  • time resolved spectroscopy and imaging
  • speckle and spatial Fourier frequencies spectroscopy for diagnoses
  • ultraviolet diagnostic methods
  • infrared diagnostic methods
  • optical biopsy mapping with linear excitation methods
  • nonlinear optical biopsy mapping
  • instrumentation for in-vivo optical biopsy
  • video spectral imaging and mapping of tissue
  • nano particle tagging and contrast agents
  • chemo- and molecular targeting agents
  • STED nano-scale imaging
  • supercontinuum for medical and biological applications
  • noninvasive detection and imaging of cancer
  • diabetes noninvasive detection
  • assessment of tissue injury
  • high resolution imaging methods for in vivo pathology
  • instrumentation of in vivo optical biopsy
  • in vivo spectroscopy and imaging
  • endoscopes and micro-endoscopes for optical biopsy
  • tissue modification with light pulses
  • laser tissue welding and real time monitoring
  • integration of optical detection and therapy systems
  • dynamics of laser-tissue interactions
  • novel methods for optical biopsy.
  • “optical metabolomics” maybe a future growth area.
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